http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018521321-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4703 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2821 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 2016-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2018521321-A |
| titleOfInvention | How to determine the risk of developing Alzheimer's disease |
| abstract | The invention relates to an in vitro method for determining the risk of developing Alzheimer's disease or a cognitive disorder similar to said disease, an in vitro design method for personalized therapy in a subject suffering from mild cognitive impairment, and an E2F4 protein or Patients sensitive to treatment with therapy for prevention and / or treatment of Alzheimer's disease or cognitive impairment similar to said disease based on determining the level of phosphorylation at the threonine residue of a functionally equivalent variant To an in vitro selection method. The present invention also relates to the use of threonine phosphorylated E2F4 or a functionally equivalent variant thereof as a marker for the risk of developing Alzheimer's disease or cognitive impairment similar to Alzheimer's disease. Finally, the present invention also relates to a kit comprising a reagent that can determine the level of phosphorylation at the threonine residue of the E2F4 protein, and the use of said kit. |
| priorityDate | 2015-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 75.