| abstract |
The present invention comprises (a) xanthohumol having the formula (1) and (b) at least one isomerized hop acid, preferably isoalpha acid (in either case concentrated or isolated form) ) Based material comprising a mixture of Surprisingly, the substance, wherein xanthohumol and isoalpha acid are present in combination, each substance present in a concentrated or isolated form in the combination is xanthofumol. It has been shown to substantially increase the efficacy associated with the prevention and / or control of liver disease or damage when compared to mall alone. Thus, surprisingly, the inflammation and fibrosis inhibitory effects of xanthohumol and the inhibition of hepatocyte fat changes are enhanced by the presence of isoalpha acids. [Selection] FIG. |