| abstract |
Compounds of formula (I) in which E 1 , E 2 , E 3 , E 4 , L 1 , Y 1 , Y 2 , Y 3 , R a and z have the meanings indicated in the specification ), And pharmaceutically acceptable salts thereof. The compound, inhibition of leukotriene C 4 synthase is desirable, and / or required treatment of disease, in particular, useful in the treatment of respiratory diseases and inflammation. [Chemical 1] |