| abstract |
The present invention relates to polypeptides comprising a CD4 binding moiety, a gp41 binding moiety, an HIV fusion peptide inhibitor moiety, and combinations thereof. More specifically, the present invention relates to a polypeptide comprising a fibronectin based scaffold domain protein that binds to CD4, a fibronectin based scaffold domain protein that binds to the N17 domain of gp41, and an HIV fusion peptide inhibitor, or combinations thereof. . The invention also relates to the use of innovative proteins in therapeutic applications to treat HIV. [Selection] Figure 1 |