| abstract |
Provided herein are novel binding domain-containing polypeptides (DBDpp) that specifically bind to a target of interest. Also provided are nucleic acids encoding DBDpp, and vectors and host cells containing said nucleic acids. Also encompassed are DBDpp libraries, methods for generating and screening such libraries, and DBDpp identified from such libraries and screens. In addition, methods for making and using DBDpp are provided. Such uses include, but are not limited to affinity purification and diagnostic and therapeutic applications. |