http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018515517-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1232 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-245 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 |
| filingDate | 2016-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2018515517-A |
| titleOfInvention | Compositions and methods for the treatment and prevention of uropathogenic E. coli infections |
| abstract | For example, using a method and antibody composition to move mannose from the binding pocket of pilus adhesin FimH of enteric bacteria of uropathogenic E. coli, Klebsiella oxytoca or Klebsiella pneumoniae (Klebsiella pneumoniae), It can prevent or prevent bacterial monolayers from attaching to the mannose-coated surface, or prevent or prevent multilayer biofilms from forming. Thus, the antibody composition of the present invention is used in various methods to inhibit, prevent or prevent surface colonization by enterobacteria expressing bacterial type 1 pili adhesin FimH, among other uses. For example, can inhibit or prevent infection of cells by enterobacteria expressing bacterial type 1 pili adhesin FimH such as uropathogenic E. coli Bacterial infections can be treated in a subject and inflammatory bowel disease (IBD) can be treated or prevented. [Selection] Figure 12 |
| priorityDate | 2015-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1179.