http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018512134-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-90258 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5067 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-06 |
| filingDate | 2016-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2018512134-A |
| titleOfInvention | A method for characterizing time-series liver toxicity |
| abstract | Methods are provided for characterizing the time-series hepatotoxicity of test compounds. In some embodiments, the method comprises the steps of a) incubating a first in vitro culture comprising hepatocytes with a test compound during a first culture period, b) the first culture period over the first culture period. Measuring at least one cytotoxic effect of the test compound on the hepatocytes of one in vitro culture, thereby defining the hepatotoxicity of the test compound over the first culture period, c) the first Incubating a second in vitro culture containing hepatocytes with the test compound for a second culture period longer than one culture period. |
| priorityDate | 2015-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 996.