Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-062 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0058 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-405 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0793 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
filingDate |
2016-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2018-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2018509909-A |
titleOfInvention |
Anion channel rhodopsin compositions and methods of use |
abstract |
Methods and compositions used to identify and characterize a new class of algae-derived rhodopsins that are highly sensitive and highly efficient anion conducting channel rhodopsins. The rhodopsin domains of these anion-conducting channel rhodopsins have been cloned and expressed in mammalian systems and are therefore used, inter alia, for optogenetic applications and as a therapeutic agent for disorders mediated by electrically active cells. can do. Described herein is a new family of photoswitchable anion channels, anion channels, that provide highly sensitive and efficient membrane hyperpolarization and neuronal silencing through photoswitchable chloride ion conduction. Rhodopsin (ACR). [Selection figure] None |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021193732-A1 |
priorityDate |
2015-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |