| abstract |
The present disclosure provides hNGAL muteins that bind to Ang-2 and can be used in a variety of applications including, for example, pharmaceutical applications to inhibit or reduce angiogenesis. The present disclosure also relates to methods of making one or more muteins described herein and compositions and combinations comprising one or more such muteins. The present disclosure further relates to nucleic acid molecules encoding such muteins and methods for making such muteins and nucleic acid molecules. The application further discloses the therapeutic and / or diagnostic uses of these muteins and compositions and combinations comprising one or more such muteins. |