| abstract |
Breton tyrosine kinase (Btk) inhibitor 1-((R) -3- (4-amino-3- (4-phenoxyphenyl) -1H-pyrazolo [3,4-d] pyrimidin-1-yl) piperidine- A co-crystal of 1-yl) prop-2-en-1-one comprising a crystalline form and pharmaceutically acceptable salts thereof is disclosed. Also, pharmaceutical compositions comprising the co-crystal and the co-crystal alone or other for the treatment of autoimmune disease or condition, heterogeneous immune disease or condition, cancer including lymphoma, and inflammatory disease or condition. Also disclosed are methods of use in combination with therapeutic agents. [Selection] Figure 1 |