http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018508223-A
Outgoing Links
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-80 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15 |
filingDate | 2016-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2018508223-A |
titleOfInvention | A system for stable gene expression |
abstract | An inducible expression cassette for the controlled expression of a plurality of genes comprises a DNA sequence of a bidirectional promoter inserted between two DNA sequences. Transfection of host cells with two DNA sequences encoding the gene of interest results in manipulation of constitutive expression of one DNA sequence and expression of the other DNA sequence. Also disclosed is a regulatory DNA cassette comprising another bi-directional promoter and two DNA sequences encoding a marker and a regulatory expression product. Both cassettes can be incorporated into non-viral or viral vectors, such as Sleeping Beauty Transposons, and can induce controlled expression of multiple genes in host cells. In addition, a kit including the above-described package of each vector type is also disclosed, and a host cell transformation method is also disclosed. |
priorityDate | 2015-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 441.