| abstract |
Compounds of formula (I) and salts thereof: (Wherein R 1 , R 2 , R 3 , R 4 are defined herein). Compounds of formula (I) and salts thereof have been confirmed to inhibit binding of the BET family of bromodomain proteins, for example to acetylated lysine residues, and thus include, for example, autoimmune and inflammatory diseases such as It may have use in therapy such as rheumatoid arthritis, as well as in the treatment of cancer. |