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filingDate 2016-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2018506533-A
titleOfInvention Combination therapy using CD19-ADC and vincristine
abstract The present invention relates to the treatment of acute lymphoblastic leukemia. A method of treating a patient having acute lymphoblastic leukemia (ALL), said method comprising administering to said subject a drug combination consisting essentially of a CD19 antibody drug conjugate (CD19-ADC) and vincristine. Wherein said CD19-ADC comprises a humanized hBU12 antibody conjugated to a maleimidocaproyl monomethyl auristatin F (mcMMAF) molecule. [Selection] Figure 6
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