| abstract |
Provided herein are methods relating to therapeutic strategies for the treatment of cancer, including hematological malignancies. In particular, the method includes administration of entspretinib and Bcl-2 inhibitors, such as Venetocrax, Navitocrax, and ABT-737. Provided herein is a method for treating cancer comprising administration of a Syk inhibitor in combination with a Bcl-2 inhibitor. In some aspects, a method for treating cancer in a human in need of treating cancer, wherein a therapeutically effective amount of a Syk inhibitor and a therapeutically effective amount of a Bcl-2 inhibitor are administered to the human. A method comprising administering is provided. |