| abstract |
In one embodiment, the present invention treats traumatic CNS injury, neurodegenerative disease, and / or autoimmune disease, and / or developmental disorder, and / or metabolic disease, increases BDNF, or moderates disease progression or symptoms In order to provide relief, a method of treatment is provided by administering DNP in a dosage range of 0.01 mg / kg body weight to less than 10 mg / kg body weight. DNP was administered daily to mice over various doses, after which a dose-dependent and non-linear increase in BDNF expression in the brain was shown. |