abstract |
A method of forming a microneedle array can include forming a microneedle array having one or more chemotherapeutic agents. The microneedle array can include a base and a plurality of microneedles extending from the base, wherein one or more chemotherapeutic agents are present at a higher concentration in the plurality of microneedles than the base. obtain. The systems and methods disclosed herein include skin delivery platforms based on dissolvable microneedle arrays that can provide efficient, accurate and reproducible delivery of biologically active molecules to human skin. The microneedle array delivery platform can be used to deliver a wide range of bioactive ingredients to patients, including the chemotherapeutic agents described herein for cancer treatment applications. |