http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018500937-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-20 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6874 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2015-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2018500937-A |
| titleOfInvention | Compositions and methods for targeted depletion, enrichment and resolution of nucleic acids using CRISPR / CAS-based proteins |
| abstract | Provided herein are methods and compositions for depleting targeted nucleic acid sequences from a sample, enriching for a sequence of interest from a sample, and / or splitting a sequence from a sample. In one aspect, a method for enriching a sample for a sequence of interest comprising: (a) providing a sample comprising a sequence of interest and a targeting sequence for depletion, wherein the sequence of interest comprises: Constituting less than 30%; (b) contacting the sample with a plurality of CRISPR / Cas system protein-gRNA complexes, wherein the gRNA is complementary to the targeting sequence and thereby targeted A method is provided herein comprising the step of cleaving the sequence. In any of the embodiments disclosed herein, the method further comprises extracting a sequence of interest and a targeting sequence for depletion from the sample. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020534863-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7006873-B2 |
| priorityDate | 2014-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 113.