| abstract |
Disclosed is a microneedle having a sharp tip or pointed tip without breaking or chipping. A substrate sheet and a plurality of microneedles on the substrate sheet, wherein at least one of the microneedles includes a plurality of portions including a distal end portion and a proximal end portion, the distal end Portion 4 comprises a first composition, said proximal end portion 5 comprises a second composition, said first composition and said second composition being different, said first composition Is a microneedle sheet 8 comprising at least one alkaline earth metal salt. A microneedle having a good shape can be provided, the proximal end portion 5 can be homogeneous and / or the microneedle sheet 8 can be distorted. [Selection] Figure 3 |