abstract |
The present invention is to provide polymorphic forms of ARRY-380, selective ERBB2 (HER2) inhibitors, and pharmaceutical compositions containing them. SOLUTION: N4- (4-([1,2,4] triazolo [1,5-a] pyridin-7-yloxy) -3-methylphenyl) -N6- (4,4-dimethyl-4,5) Polymorphs of-dihydrooxazol-2-yl) quinazoline-4,6-diamine are provided herein. In addition, N4- (4-([1,2,4] triazolo [1,5-a] pyridin-7-yloxy) -3-methylphenyl) -N6- (4,4-dimethyl-4,5-dihydro). Provided herein are pharmaceutical compositions comprising polymorphs of oxazol-2-yl) quinazoline-4,6-diamine, and processes for preparing those polymorphs. 【Selection chart】 None |