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publicationDate 2018-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2018173361-A
titleOfInvention Method for producing probe binding carrier, probe binding carrier and method for detecting or separating target substance
abstract To provide a probe-binding carrier capable of expressing a high S / N ratio at the time of diagnosis or detection, and a method for producing the carrier, with less non-specific adsorption of biologically relevant substances such as proteins and nucleic acids. An area occupied by one tosyl group on the surface of a carrier used in the step 1 includes a step 1 of mixing a carrier having a tosyl group and a probe and a step 2 of reducing the amount of a tosyl group on the surface of the carrier. The method for producing a probe-bound carrier, wherein the ratio of the area S2 occupied by one tosyl group on the surface of the carrier obtained in Step 2 to S1A (S2 / S1A × 100%) is 140% or more. [Selection figure] None
priorityDate 2017-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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