Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c9e4cedb72851f01dadac14d585e8b17 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H05K999-99 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
filingDate |
2018-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_206722d3082679fc2785420884be7e1b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f67aeb5374dc9b0ef8a8cd4bcee506a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_893834142c5bf786fb069e5fc889adef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e87fc3cc5d92684741ab7db718653b15 |
publicationDate |
2018-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2018168191-A |
titleOfInvention |
3- (imidazo [1,2-b] pyridazin-3-ylethynyl) -4-methyl-N- {4-[(4-methylpiperazin-1-yl) methyl] -3- (trifluoromethyl) phenyl} Crystalline form of benzamide and its monohydrochloride |
abstract |
3- (Imidazo [1,2-b] pyridazin-3-ylethynyl) -4-methyl is a multi-target tyrosine kinase inhibitor useful for the treatment of diseases including chronic myelogenous leukemia (CML). Provision of polymorphs of -N- {4-[(4-methylpiperazin-1-yl) methyl] -3- (trifluoromethyl) phenyl} benzamide. Novel crystalline 3- (imidazo [1,2-b] pyridazin-3-ylethynyl) -4-methyl-N- {4-[(4-methylpiperazine-1) of A-form to K-form -Yl) methyl] -3- (trifluoromethyl) phenyl} benzamide monohydrochloride. [Selection figure] None |
priorityDate |
2012-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |