| abstract |
A human antibody that specifically binds human angiopoietin-like protein 3 (hANGPTL3) is provided. An isolated human that specifically binds to human angiopoietin-like protein 3 (hANGPTL3) having a specific amino acid sequence and neutralizes, decreases, or interferes with at least one activity of hANGPTL3. Antibodies or antigen-binding fragments thereof are provided. Human anti-hANGPTL3 antibodies treat ANGPTL3-related diseases or disorders such as hyperlipidemia, including hypertriglyceridemia, hypercholesterolemia, chylomicronemia, hyperlipoproteinemia, and dyslipidemia Useful for. [Selection figure] None |