| abstract |
PROBLEM TO BE SOLVED: To provide a method for predicting whether a protein or polypeptide containing an immunoglobulin single variable domain (ISV) or at least one ISV causes protein interference in an immunoassay such as an ADA assay. (I) An antibody obtained from a human subject, which is selected / isolated based on the ability to recognize the C-terminus of the ISV and / or the ability to bind to the C-terminus of the ISV And (ii) determining whether or not the ISV, protein or polypeptide binds to the antibody in the immunoassay. Performing the assay. [Selection figure] None |