| abstract |
An object of the present invention is to provide a therapeutic agent, food and cosmetics containing hiristine as an active ingredient. A nitric oxide production promoter, a cGMP production promoter, a cGMP-dependent protein kinase gene expression enhancer, a smooth muscle relaxant, a vasodilator, a blood circulation promoter, or erectile dysfunction, pulmonary arterial pulmonary hypertension, Prostatic hypertrophy, heart failure, stroke, schizophrenia, depression, blood circulation disorder, rough skin, skin disorders, cartilage abnormalities such as achondroplasia and hypocartilaginous dysplasia, squamous cell carcinoma, stomach cancer, colon cancer, thyroid cancer, A therapeutic agent or the like for treating a disease selected from a group consisting of tumors such as prostate cancer, and the like, has hirstine as an active ingredient, and therapeutic agents, foods and cosmetics containing those agents. [Selection figure] None |