abstract |
The present invention provides a composition containing a compound having a strong astrocyte differentiation promoting action. A pharmaceutical composition or food composition containing a coronaline derivative represented by formula (I) or a solvate thereof. (R 1 is H or OH; XY is CH 2 —CH 2 , CH═CH or CH 2 —CH═ or XY is not included, R 2 and decahydronaphthalene ring are directly bonded; R 2 is furan ring , Dihydrofuran ring, etc.) [Selection] Figure 5 |