abstract |
As an alternative dosage form comprising a 3- (3-dimethylamino-1-ethyl-2-methyl-propyl) -phenolic compound such as tapentadol capable of achieving a controlled release of the active substance, in particular in solid form Providing a 3- (3-dimethylamino-1-ethyl-2-methyl-propyl) -phenolic compound for use in the treatment of pain, for example in a form suitable for oral administration. 3- (3-Dimethylamino-1-ethyl-2-methyl-propyl) -phenol (component a) and at least one acid component (b1) or at least one acid component (b2) ) Salt or co-crystal (wherein the salt or co-crystal of component (a) and component (b2) exists in crystalline and / or amorphous form). [Selection figure] None |