abstract |
Acetaminophen conjugates and compositions thereof and methods of use thereof are provided. An acetaminophen conjugate having an acetaminophen moiety covalently attached to a second moiety is provided. Provided conjugates may have one or more advantageous properties including high aqueous solubility compared to acetaminophen, a low toxicity profile compared to acetaminophen, and a modified pharmacokinetic profile . Similar to methods of using the conjugate and kits containing the conjugate, formulations containing the conjugate are also provided. [Selection figure] None |