| abstract |
A composition for treating cancer is provided. The present invention relates to a zwitterionic liposome consisting essentially of 50-70 mol% phosphatidylcholine lipid, 25-45 mol% cholesterol, and 2-8 mol% PEG-lipid; and oxaliplatin Compositions for the treatment of cancer comprising are provided. Oxaliplatin is encapsulated in the liposomes in an amount such that the ratio of total lipid weight to oxytilplatin weight is from about 20: 1 to about 65: 1. Also disclosed are methods of preparing liposomal oxaliplatin and methods for the treatment of cancer. [Selection figure] None |