http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018095561-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0806cdd1c8162f7844aacff67da1cf43 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-08 |
filingDate | 2016-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30573de9961cf5d0ab0a9536e89a7280 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7aa7b4c1e02f2c0303a38e64556ce793 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05866cb2be34150a5cfde0761c01550e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4997163a85cde473ced72920f35c4c16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf94aaed77646f0e48071df6843aae1c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_271c840cb0b3aeb41579a55dc6d42648 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3a81b577a244d7c83383e4c3a770228 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b78be3840cbdfbdb70f9d8baf2aece9 |
publicationDate | 2018-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2018095561-A |
titleOfInvention | Method for producing diphenylazetidine derivative |
abstract | To provide a highly efficient industrial production method of a diphenylazetidine derivative which is a raw material for producing a β-lactam derivative useful for the treatment and prevention of hypercholesterolemia such as arteriosclerosis. The general formula (I) [wherein R is a branched lower alkyl group, an allyl group, a lower alkyl group containing a lower alkoxy group, a lower alkyl group containing a lower thioalkyl group, a tetrahydropyranyl group, A triphenylmethyl group, a silyl group having a substituent, a phenyl group which may have a substituent, and a benzyl group which may have a substituent are shown. And a compound represented by the general formula (II) [wherein M represents MgCl, MgBr, MgI, Li. The compound represented by the general formula (III) is obtained by reacting the compound represented by formula (II) in a toluene solvent: wherein R is the same as in the general formula (I). ] The manufacturing method of the compound represented by this. [Selection figure] None |
priorityDate | 2016-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.