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publicationDate 2018-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2018070647-A
titleOfInvention Easy to take and split tablet
abstract [PROBLEMS] Even a large tablet containing a high content of levofloxacin, which is a quinolone synthetic antibacterial agent with excellent antibacterial activity and high safety, is not difficult to take in actual use and difficult to take in appearance Provide tablets that do not give the impression. An oval tablet having a mass of 570 to 700 mg, containing 500 mg of levofloxacin hemihydrate crystals as levofloxacin, and having a major axis / minor axis ratio of 2.00 to 2.50 and a major axis The dividing line with a depth in the range of 0.7-1.5mm is tablet so that the tablet hardness is 50-280N and the area of the fracture surface of the tablet when it is divided by the dividing line is 15-33mm 2 Tablets on both sides. A tablet obtained by preparing granules containing repofloxacin, adding a lubricant, and applying a film coating to the raw material obtained by tableting. [Selection figure] None
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