| abstract |
The present invention provides a compound effective in inhibiting the function of the nonstructural protein NS5A, which is an essential component in the replication of hepatitis C virus ("HCV"). Methyl {(2S, 3R) -1-[(2S) -2- {5-[(2R, 5R) -1- {3,5-difluoro-4- [4- (4-fluorophenyl) ) Piperidin-1-yl] phenyl} -5- (6-fluoro-2-{(2S) -1- [N- (methoxycarbonyl) -O-methyl-L-threonyl] pyrrolidin-2-yl} -1H -Benzimidazol-5-yl) pyrrolidin-2-yl] -6-fluoro-1H-benzimidazol-2-yl} pyrrolidin-1-yl] -3-methoxy-1-oxobutan-2-yl} carbamate and the like Exemplified compounds, or pharmaceutically acceptable salts and derivatives thereof. [Selection figure] None |