| abstract |
[PROBLEMS] (1) Can be easily manufactured in general equipment without requiring special formulation technology, (2) Has moderate strength that does not damage during distribution, (3) Rapid disintegration in the oral cavity (4) To provide an orally disintegrating tablet having excellent characteristics such as having a good feeling of taking which greatly reduces bitterness and roughness. SOLUTION: (1) D-mannitol, (2) active ingredient, (3) one or more disintegrant selected from the group consisting of crospovidone and carmellose, (4) sucrose fatty acid ester, (5) binder , And (6) Contains starch, the content of D-mannitol in the preparation is 50% by weight or more, An orally disintegrating tablet that disintegrates within 30 seconds and has an absolute hardness of 2.5 N / mm 2 . [Selection figure] None |