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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-675
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filingDate 2018-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8e9aa9c037306f6e876e0ead0719b68
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publicationDate 2018-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2018058909-A
titleOfInvention Pharmaceutical composition for oral administration
abstract The present invention relates to a pharmaceutical tablet containing minodronic acid or a pharmaceutically acceptable salt or hydrate thereof useful as a therapeutic agent for osteoporosis, which has improved drug dissolution, tablet hardness, wrinkle adhesion and the like. A dosage formulation is provided. The pharmaceutical tablet comprises 50 mg or 60 mg of minodronic acid or a pharmaceutically acceptable salt or hydrate thereof in the pharmaceutical tablet, and croscarmellose sodium, crospovidone, and carboxymethyl starch sodium. 1 or two or more substances selected from the group consisting of: Minodronic acid or a pharmaceutically acceptable salt thereof or a hydrate thereof was measured by a laser diffraction method described in Japanese Pharmacopoeia The average particle diameter D 50 is 1 μm or more and 20 μm or less, and the drug dissolution rate 15 minutes after the start of the dissolution test is 80% or more. [Selection figure] None
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112972400-A
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priorityDate 2011-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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