| abstract |
[PROBLEMS] To improve the productivity of a method for producing a betalain dye or the like using microorganisms. A tyrosinase activity having a specific amino acid sequence or an amino acid sequence having 90% or more identity with a specific amino acid sequence, and having the following mutation (i) and / or (ii) protein. (I) S2, N3, Y5, I28, K30, G46, F48, S54, N57, W68, E71, S104, D127, N144, D166, D170, K173, W182, E187, N188, S189 in a specific amino acid sequence Amino acid residues corresponding to one or more amino acid residues selected from the group consisting of Q193, E195, T220, H230, N233, W241, I243, Q251, N261, D264, Y267, P273, G283, and I288 are substituted. Mutations. (Ii) A mutation in which an amino acid residue corresponding to V218 in a specific amino acid sequence is substituted. [Selection figure] None |