| abstract |
An implantable device and method for evaluating an active agent is provided. A device for local delivery of a microdose of one or more active agents to a selected tissue of a patient at one or more doses, alone or in combination, is described. The device generally includes a plurality of microwells disposed on or within the support structure. The microwell contains one or more active agents, alone or in combination, in one or more doses and / or release pharmacokinetics. In an exemplary embodiment, the device has a cylindrical shape and has symmetric wells outside the device, each well comprising one or more drugs at one or more concentrations, and a catheter Sized to allow placement using a cannula or stylet. [Selection figure] None |