| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b1e472e52510b9a0150fb8bb983e5c5a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-314
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-353
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-351
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-346
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3513
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3233 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65616
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65583
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65586
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1131
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65846
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-09 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6584
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-675
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2017-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_feafe57c175306ddab789eab6b8cfa68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53f4b93cfc1f234cda458ef3fd68df12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a796160f6d116ae0c8a95a3ba0ee5fa8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_799cf87bfd42eb86838f6b3ee3cc350c |
| publicationDate |
2018-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2018048208-A |
| titleOfInvention |
Functionally modified oligonucleotides and subunits thereof |
| abstract |
Functionally modified oligonucleotide analogs comprising modified intersubunit linkages and / or modified 3 'and / or 5' end groups. The disclosed compounds are useful in the treatment of diseases, where inhibition of protein expression or modulation of aberrant mRNA splice products results in beneficial therapeutic effects. In one embodiment, a compound comprising a backbone comprising a sequence of morpholino ring structures connected by an intersubunit linkage connecting the 3 ′ end of a morpholino ring structure to the 5 ′ end of an adjacent morpholino ring structure, each Described herein are compounds in which the morpholino ring structure is attached to a base-pairing moiety and the compound can bind to a target nucleic acid in a sequence specific manner. [Selection figure] None |
| priorityDate |
2011-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |