abstract |
A neuromuscular blocking compound is provided. A pharmaceutical composition comprising a biocompatible solvent and a compound represented by formula (I). A pharmaceutical composition comprising a compound of formula (I), wherein the biocompatible solvent comprises 0.9% saline, the pH is about 2.5 to 3.5, and the concentration is about 1 to about 10 mg / mL. object. A kit comprising said pharmaceutical composition and a second container thiol compound in a first container. The alcohol having the right end or the left end of formula (I) is reacted with maleic anhydride or dichlorosuccinic anhydride, and the resulting reaction product is reacted with alcohol at the other end to be represented by formula (I) A method for producing a compound. [Selection] Figure 4 |