http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018023355-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_be4eba9539585114cd0e90a237a5246a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_19d47a9a7350624411cfa37a23b9bba1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c00f13e338e8dc36579ece14574d71ab |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2016-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6819685d67911bfff938d8b7df137ea7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_787d48e22151ee1d01c0ef24ca460a14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44c87e2c72b7c9a4ff3e5782441da2ee |
publicationDate | 2018-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2018023355-A |
titleOfInvention | Assistance for risk assessment of non-Hodgkin lymphoma development |
abstract | Provided is a method capable of effectively and appropriately determining the risk of developing non-Hodgkin lymphoma including ATLL. At least one of the presence or absence of a G7340A mutation, a G7322A mutation, and a G7467A mutation in a HTLV-1 gene of a subject is detected. Non-Hodgkin lymphoma is adult T-cell leukemia lymphoma (ATLL). It is preferable to detect the presence or absence of HLA-A * 02 positive in the subject. ATLL carriers are in a balanced state of growth-promoting action by viral genes (Tax and HBZ) and inhibitory action by host immunity (mainly Tax-specific CTL). Is seen. For example, when the G7340A mutation is present, the expression of Tax is low and the expression of HBZ is high. [Selection] Figure 4 |
priorityDate | 2016-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.