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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
filingDate 2016-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6819685d67911bfff938d8b7df137ea7
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publicationDate 2018-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2018023355-A
titleOfInvention Assistance for risk assessment of non-Hodgkin lymphoma development
abstract Provided is a method capable of effectively and appropriately determining the risk of developing non-Hodgkin lymphoma including ATLL. At least one of the presence or absence of a G7340A mutation, a G7322A mutation, and a G7467A mutation in a HTLV-1 gene of a subject is detected. Non-Hodgkin lymphoma is adult T-cell leukemia lymphoma (ATLL). It is preferable to detect the presence or absence of HLA-A * 02 positive in the subject. ATLL carriers are in a balanced state of growth-promoting action by viral genes (Tax and HBZ) and inhibitory action by host immunity (mainly Tax-specific CTL). Is seen. For example, when the G7340A mutation is present, the expression of Tax is low and the expression of HBZ is high. [Selection] Figure 4
priorityDate 2016-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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