| abstract |
A cyclodextrin-based polymer for delivery of a therapeutic agent. Methods are provided relating to the use of CDP-therapeutic agent conjugates for the treatment of diseases or disorders such as autoimmune diseases, inflammatory diseases, central nervous system disorders, cardiovascular diseases or metabolic disorders. Also provided are CDP-therapeutic agent conjugates, particles comprising CDP-therapeutic agent conjugates and compositions comprising CDP-therapeutic agent conjugates. In one aspect, the invention features a method of treating a disease or disorder in a subject, eg, a human subject, such as an autoimmune disease, inflammatory disease, metabolic disorder, cardiovascular disorder, central nervous system disorder, the method comprising: Administration of a CDP-therapeutic agent conjugate, particle or composition to a subject, eg, a human subject, in an amount effective to treat the disease. [Selection] Figure 3 |