http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018012690-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_22ed64b8daa3bbc0ba4ebdf18e5e246f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D223-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-16 |
| filingDate | 2017-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_118a6617d193dc3e2e94821f8a75093b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9b28cfa75e0ddc06b21eb01623b5394 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3dcf8ee3e9b407e03eb3a5589ce8d292 |
| publicationDate | 2018-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2018012690-A |
| titleOfInvention | Improved process for the preparation of tolvaptan synthetic intermediates |
| abstract | The present invention provides an improved process for producing 7-chloro-1- (2-methyl-4-nitrobenzoyl) -5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine. 7-Chloro-1- [2-methyl-4-[(2-methylbenzoyl) amino, which is a synthetic intermediate of tolvaptan, which condenses an amino group and a carboxyl group in the presence of magnesium hydroxide ] Benzoyl] -5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine and 7-chloro-1- (2-methyl-4-nitrobenzoyl) -5-oxo-2,3,4 , 5-Tetrahydro-1H-1-benzazepine production method. [Selection figure] None |
| priorityDate | 2016-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 97.