abstract |
The present invention relates to benzenesulfonamide derivatives of formula (I), pharmaceutically acceptable addition salts thereof, hydrates and / or solvates thereof, and those as inverse agonists of the retinoid-related orphan receptor gamma (RORγt). About the use of. The present invention relates to pharmaceutical compositions comprising such compounds and for the topical and / or oral treatment of RORγt receptor mediated inflammatory diseases, in particular acne, psoriasis and / or atopic dermatitis. Also related to its use. |