http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017537894-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-26 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
filingDate | 2015-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2017537894-A |
titleOfInvention | Compositions and peptides having GLP-1R and GLP-2R dual agonist activity |
abstract | The present invention relates to compositions and peptides having agonist activity at both human GLP-1 receptor and human GLP-2 receptor, and relative agonist activity (GLP- 1R relative ) is at least 0.01, the relative agonist activity of the double peptide to the human GLP-2 receptor (GLP-2R relative ) is at least 0.01, and (GLP-1R relative ) (GLP -2R relative ) is at least 0.01. The present invention also relates to methods and uses of the compositions and peptides. It is also related to lipidated analogues of the above peptides. Furthermore, the present invention relates to treatment or prevention therapy for human diseases, particularly intestinal / brain related diseases and metabolic disorders, including gastrointestinal inflammation, short bowel syndrome, and Crohn's disease. [Selection figure] None |
priorityDate | 2014-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 140.