| abstract |
N-substituted phenyl-5-substituted alkoxy-2,3-dihydro- [1,4] dioxane [2,3-f] quinazoline-10-amine (I) or 4-substituted arylamino-6-substituted alkyl-6H -[1,4] oxazino [3,2-g] quinazolin-7 (8H) -one (II) compounds, methods for their preparation, application as epidermal growth factor receptor inhibitors for treating cancer, Includes several mutant forms of EGFR. These compounds and salts thereof can treat or prevent multiple types of cancer diseases. [Chemical 1] [Selection figure] None |