http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017536407-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-141 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-146 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-141 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 |
| filingDate | 2015-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2017536407-A |
| titleOfInvention | Anticancer composition |
| abstract | The present invention relates to pharmaceutical formulations of ARN-509, which formulations are androgen receptor (AR) related diseases or conditions, specifically cancer, more specifically prostate cancer, such as, but not limited to, Castration-resistant prostate cancer, metastatic castration-resistant prostate cancer, chemotherapy-naïve metastatic castration-resistant prostate cancer, biochemically recurrent hormone-sensitive positive prostate cancer, or high-risk non-metastatic castration-resistant prostate cancer Can be administered to mammals, particularly humans. In one aspect, these formulations comprise a solid dispersion of ARN-509, a poly (meth) acrylate copolymer, and HPMCAS. In one aspect, a solid dispersion of ARN-509, poly (meth) acrylate copolymer, and HPMCAS is a melt extrusion of a mixture comprising ARN-509, poly (meth) acrylate copolymer, and HPMCAS, followed by Optionally, it can be obtained, in particular obtained, by grinding the melt-extruded mixture. In one aspect, a solid dispersion of ARN-509, poly (meth) acrylate copolymer, and HPMCAS is sprayed with a mixture comprising ARN-509, poly (meth) acrylate copolymer, and HPMCAS in a suitable solvent. It can be obtained by drying and is particularly obtained. |
| priorityDate | 2014-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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