http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017536337-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 |
| filingDate | 2015-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2017536337-A |
| titleOfInvention | Biphasic single chain insulin analogues |
| abstract | Single chain insulin is a C region of 6-11 amino acid residues having at least two acidic residues on the N-terminal side of the C region and at least two basic residues on the C-terminal side of the C region peptide. And a basic amino acid residue at a position corresponding to A8 of human insulin, and an acidic amino acid residue at a position corresponding to A14 of human insulin. The C region can contain 2 to 4 amino acid junction regions between acidic and basic residues. Residues C1 and C2 can have a net negative charge of -1 or -2, and the remaining C region portion may end with two basic residues. The pharmaceutical composition has single chain insulin and is administered at a pH in the range of 7.0 to 8.0, at a concentration of 0.6 mM to 5.0 mM, and / or at an intensity of U-100 to U-1000. Can be administered. [Selection figure] None |
| priorityDate | 2014-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 170.