| abstract |
The present invention includes compounds of formula I. [Chemical 1] Where R 1 , R 2 , R 3 , R 4 , R 5 , R 7 , R 8 , and Is as defined herein. The invention also includes a compound of formula I for use in a method of treatment or amelioration of a syndrome, disorder or disease, wherein the syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also includes a compound for use in a method for modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1. |