abstract |
The present invention relates to compounds. More specifically, the present invention relates to compounds useful as inhibitors of the Wnt signaling pathway. Specifically, the present invention contemplates inhibitors of Porcupine (Porcn). In addition, the present invention contemplates methods of preparing the compounds and uses of the compounds. Thus, the compounds of the present invention treat conditions mediated by the Wnt signaling pathway, such as cancer, sarcoma, melanoma, skin cancer, blood tumor, lymphoma, carcinoma, and leukemia; or anti-cancer therapy Can be used to enhance effectiveness. |