http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017530158-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-141 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-04 |
filingDate | 2015-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2017530158-A |
titleOfInvention | Cardiomyocyte-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy |
abstract | Described herein are compositions and techniques relating to the generation and therapeutic applications of cardiomyocyte-derived cells (CDC) and CDC-derived exosomes. These cells and their secretory vesicles are biological factors including cytokines, growth factors, transcription factors, nucleic acids (including non-coding nucleic acids such as microRNAs) that initiate and promote many therapeutic effects Contains a unique environment of biological factors that work like so. Exosomes and their “cargo” contents, such as microRNAs, can advantageously modulate apoptosis, inflammation and fibrosis in the injured heart. CDC-derived exosomes are therefore novel “cell-free” therapeutic candidates for tissue repair. |
priorityDate | 2014-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 682.