| abstract |
The present disclosure includes a liposome containing an internal space, a bioactive antifolate agent disposed in the internal space, a steric stabilizer added to the outside of the liposome, and a protein having specific affinity for at least one folate receptor There is provided a liposomal antifolate composition comprising a targeting moiety comprising: wherein the targeting moiety is added to at least one of the steric stabilizer and the exterior of the liposome. [Selection figure] None |