| abstract |
The present invention provides compounds of formula I, and related compositions and methods. In formula I, R 1 and R 2 each represent a branched or unbranched carbon chain of 1-20 carbon atoms with at least one basic functional group; R 1 and R 2 are identical X 1 and X 2 are independently selected from H and —CO—Z, wherein Z is a peptide moiety comprising 1 to 5 amino acids or pharmaceutically acceptable salts thereof; X 1 and X 2 are the same or different; M is a divalent metal cation selected from magnesium (Mg 2+ ), calcium (Ca 2+ ), and zinc (Zn 2+ ); A and B are , Each molecule having at least one acidic functional group, and either A or B may be absent, but not both, and when both A and B are present, A and B are the same But different It may be. In certain embodiments, at least one or both of “A” and “B” is a fatty acid. A representative example of the present application is the compound shown after the formula, magnesium lysinate bisdocosapentaenoic acid; the complex of the present application treats pathological conditions responsive to treatment with polyunsaturated fatty acids, particularly as a pharmaceutical composition or food additive. Used to do. [Selection figure] None |